A detailed description of the tunnel parameters can be found in a separate article.
Note:
176.53.182.35 – external IP-address of your Edge Gateway
10.10.10.0/24 – local network connected to your Edge Gateway
176.53.182.58 – external IP-address of your router Mikrotik
10.0.0.0/24 – local network connected to your Mikrotik
Connection setup is carried out in 2 stages.
Stage №1: Hardware Setup Mikrotik.
Stage №2: Configure Edge Gateway on a remote server.
Stage №1
On the tab «IP» in the drop down menu choose «IPsec» .
Choose the tab «Peers» and click «Add new» to add new connection.
In the window that opens, enter the following values:
Name - Connection name
Address – external IP-address your Edge Gateway
Local Address – external IP-address your router Mikrotik
Exchange Mode – IKE2
Go to the tab «Proposals» and click «Add new»
In the field "Name" specify the name:
Auth. Algorithms – choose sha256
Encr. Algorithms – tick aes-256 cbc
PFS Group – choose modp2048
Go to the tab «Identities» and click «Add new»
In the field «Peer» choose the earlier created connection.
In the field «Auth. Method» choose the value pre shared key
In the field «Secret» enter a password for the connection. Please, write down the password. You will need it during the Stage #2.
In the field «Notrack Chain» choose the value prerouting
Go to the value «Policies» and click «Add new»
In the field «Peer» choose the earlier created connection.
Tick the parameter«Tunnel».
«Src. Address» - local network address connected to your Mikrotik
«Dst. Address» - local network address connected to your Edge Gateway
In the field «Action» choose encrypt
In the field «Level» choose require
In the field «IPsec Protocols» choose esp
In the field «Proposal» choose the earlier created profile
Go to the tab «Profiles» and click on «default»
Change the settings to the following values
Hash Algorithms – sha256
Encryption Algorithm – aes-256
DH Group - modp2048
Go to the sub menu «Firewall» to the tab «Filter Rules» and click «Add New»
In the field «Chain» choose the value forward
In the field «Src. Address» enter the local network address connected to your Edge Gateway
In the field «Dst. Address» enter the local network address connected to your Mikrotik
On the tab «Action» choose the value accept 
Repeat the steps to add the rule to Firewall, but in «Src. Address» enter the local network address connected to your Mikrotik, in «Dst. Address» enter the local network address connected to your Edge Gateway.
Go to the tab «NAT» and click «Add New» to choose a new rule.
In the field «Chain» choose the value forward
In the field «Src. Address» enter the local network address connected to your Mikrotik
In the field «Dst. Address» enter the local network address connected to your Edge Gateway
Choose another rule. Change the values of «Src. Address» and «Dst. Address».
The result should be two “mirror" rules.
Go to the tab «RAW» and click «Add New»
In the field «Chain» choose the value prerouting
In the field «Src. Address» enter the local network address connected to your Mikrotik
In the field «Dst. Address» enter the local network address connected to your Edge Gateway
Create one more rule, where in the field «Src. Address» enter the local network address connected to your Edge Gateway, and in the field «Dst. Address» enter the local network address connected to your Mikrotik.
The result should be two “mirror" rules.
Stage №2
Go to your personal account and select the desired Datacenter.
.
In the menu «Networking» choose the sub menu «Edges»
Select your connection and click CONFIGURE SERVICES
In the window that opens, go to the "VPN" tab.
Chose the sub tab «IPsec VPN» and go to the sub menu «IPsec VPN Sites»
Click «+» to set up the connection.
In the window that appears, move the “Enabled” slider to the active state, “Enable perfect forward secrecy (PFS)” must be disabled, because. when this option is enabled, problems are observed, the tunnel may fall, we recommend disabling PFS.In the field «Name» enter the name of your connection.
In the field «Local Id» и «Local Endpoint» enter external IP-address to your Edge Gateway
In the field «Local Subnets» enter the local network address connected to your Edge Gateway
In the field «Peer Id» и «Peer Endpoint» enter external IP-address to your router Mikrotik
In the field «Peer Subnets» enter the local network address connected to your Mikrotik.
Choose the following settings:
Encryption Algorithm – AES256
Authentication – PSK
In the field «Pre-Shared Key» enter the password (that you wrote down). You have already entered it in the Mikrotik settings in the field «Secret». 
Choose the following settings:
Diffie-Hellman Group – DH14
Digest Algorithm – SHA-256
IKE Option – IKEv2
Session Type – Policy Based Session
Click «Keep» to save the changes.
Go to the tab «Activation Status» and activate «IPsec VPN Service Status»
